Journal: 3 Biotech

Article Title: Functional analysis of selected deletion mutants in Candida glabrata under hypoxia

doi: 10.1007/s13205-017-0821-7

Figure Lengend Snippet: C. glabrata strains used in this study

Article Snippet: Interestingly, no change in antifungal susceptibility of biofilm was observed for cch1 ∆, atm1 ∆ and upc2B ∆ (Table ). table ft1 table-wrap mode="anchored" t5 Table 4 caption a7 Sr. no. Strain Percent RRMA* under normoxia Percent RRMA* under hypoxia 1 pdr1 Δ 11.00 23.48 2 cch1 Δ 39.00 38.19 3 upc2B Δ 45.15 49.66 cdr1 Δ 27.64 20.18 5 ecm33 Δ 26.96 32.20 6 mid1 Δ Nil 32.92 7 kre1 Δ 04.52 31.32 8 atm1 Δ 15.58 14.02 9 rox1 Δ 11.01 34.59 10 kre2 Δ 20.36 46.14 11 ecm7 Δ 18.14 46.35 12 dun1 Δ 12.62 21.02 13 erg5 Δ 03.14 23.11 Open in a separate window * Percent RRMA relative reduction in the mean metabolic activity of biofilm in percent, with reference to the mean metabolic activity of wild-type strain, ATCC 2001 Reduction in metabolic activities of biofilm of deletion mutants when compared with the control in the presence of 16 μg ml −1 fluconazole When compared with the normoxic results, hypoxia highly increased the biofilm susceptibility to FLU for pdr1 ∆, mid1 ∆, kre1 ∆, rox1 ∆, kre2 ∆, ecm7 ∆, dun1 ∆ and erg5 ∆ deletion mutants.

Techniques:

Journal: 3 Biotech

Article Title: Functional analysis of selected deletion mutants in Candida glabrata under hypoxia

doi: 10.1007/s13205-017-0821-7

Figure Lengend Snippet: IC 50 of fluconazole for the strains under normoxia and hypoxia

Article Snippet: Interestingly, no change in antifungal susceptibility of biofilm was observed for cch1 ∆, atm1 ∆ and upc2B ∆ (Table ). table ft1 table-wrap mode="anchored" t5 Table 4 caption a7 Sr. no. Strain Percent RRMA* under normoxia Percent RRMA* under hypoxia 1 pdr1 Δ 11.00 23.48 2 cch1 Δ 39.00 38.19 3 upc2B Δ 45.15 49.66 cdr1 Δ 27.64 20.18 5 ecm33 Δ 26.96 32.20 6 mid1 Δ Nil 32.92 7 kre1 Δ 04.52 31.32 8 atm1 Δ 15.58 14.02 9 rox1 Δ 11.01 34.59 10 kre2 Δ 20.36 46.14 11 ecm7 Δ 18.14 46.35 12 dun1 Δ 12.62 21.02 13 erg5 Δ 03.14 23.11 Open in a separate window * Percent RRMA relative reduction in the mean metabolic activity of biofilm in percent, with reference to the mean metabolic activity of wild-type strain, ATCC 2001 Reduction in metabolic activities of biofilm of deletion mutants when compared with the control in the presence of 16 μg ml −1 fluconazole When compared with the normoxic results, hypoxia highly increased the biofilm susceptibility to FLU for pdr1 ∆, mid1 ∆, kre1 ∆, rox1 ∆, kre2 ∆, ecm7 ∆, dun1 ∆ and erg5 ∆ deletion mutants.

Techniques:

Journal: 3 Biotech

Article Title: Functional analysis of selected deletion mutants in Candida glabrata under hypoxia

doi: 10.1007/s13205-017-0821-7

Figure Lengend Snippet: Mean value of O.D. 492nm for biofilm of deletion mutants

Article Snippet: Interestingly, no change in antifungal susceptibility of biofilm was observed for cch1 ∆, atm1 ∆ and upc2B ∆ (Table ). table ft1 table-wrap mode="anchored" t5 Table 4 caption a7 Sr. no. Strain Percent RRMA* under normoxia Percent RRMA* under hypoxia 1 pdr1 Δ 11.00 23.48 2 cch1 Δ 39.00 38.19 3 upc2B Δ 45.15 49.66 cdr1 Δ 27.64 20.18 5 ecm33 Δ 26.96 32.20 6 mid1 Δ Nil 32.92 7 kre1 Δ 04.52 31.32 8 atm1 Δ 15.58 14.02 9 rox1 Δ 11.01 34.59 10 kre2 Δ 20.36 46.14 11 ecm7 Δ 18.14 46.35 12 dun1 Δ 12.62 21.02 13 erg5 Δ 03.14 23.11 Open in a separate window * Percent RRMA relative reduction in the mean metabolic activity of biofilm in percent, with reference to the mean metabolic activity of wild-type strain, ATCC 2001 Reduction in metabolic activities of biofilm of deletion mutants when compared with the control in the presence of 16 μg ml −1 fluconazole When compared with the normoxic results, hypoxia highly increased the biofilm susceptibility to FLU for pdr1 ∆, mid1 ∆, kre1 ∆, rox1 ∆, kre2 ∆, ecm7 ∆, dun1 ∆ and erg5 ∆ deletion mutants.

Techniques:

Journal: 3 Biotech

Article Title: Functional analysis of selected deletion mutants in Candida glabrata under hypoxia

doi: 10.1007/s13205-017-0821-7

Figure Lengend Snippet: Reduction in metabolic activities of biofilm of deletion mutants when compared with the control in the presence of 16 μg ml −1 fluconazole

Article Snippet: Interestingly, no change in antifungal susceptibility of biofilm was observed for cch1 ∆, atm1 ∆ and upc2B ∆ (Table ). table ft1 table-wrap mode="anchored" t5 Table 4 caption a7 Sr. no. Strain Percent RRMA* under normoxia Percent RRMA* under hypoxia 1 pdr1 Δ 11.00 23.48 2 cch1 Δ 39.00 38.19 3 upc2B Δ 45.15 49.66 cdr1 Δ 27.64 20.18 5 ecm33 Δ 26.96 32.20 6 mid1 Δ Nil 32.92 7 kre1 Δ 04.52 31.32 8 atm1 Δ 15.58 14.02 9 rox1 Δ 11.01 34.59 10 kre2 Δ 20.36 46.14 11 ecm7 Δ 18.14 46.35 12 dun1 Δ 12.62 21.02 13 erg5 Δ 03.14 23.11 Open in a separate window * Percent RRMA relative reduction in the mean metabolic activity of biofilm in percent, with reference to the mean metabolic activity of wild-type strain, ATCC 2001 Reduction in metabolic activities of biofilm of deletion mutants when compared with the control in the presence of 16 μg ml −1 fluconazole When compared with the normoxic results, hypoxia highly increased the biofilm susceptibility to FLU for pdr1 ∆, mid1 ∆, kre1 ∆, rox1 ∆, kre2 ∆, ecm7 ∆, dun1 ∆ and erg5 ∆ deletion mutants.

Techniques: Control